Protein Info for GFF2207 in Variovorax sp. SCN45

Annotation: Flp pilus assembly protein TadB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 98 to 122 (25 residues), see Phobius details amino acids 128 to 149 (22 residues), see Phobius details amino acids 275 to 297 (23 residues), see Phobius details amino acids 309 to 329 (21 residues), see Phobius details PF00482: T2SSF" amino acids 166 to 291 (126 residues), 43.2 bits, see alignment E=1.8e-15

Best Hits

KEGG orthology group: K12510, tight adherence protein B (inferred from 65% identity to vpe:Varpa_5154)

Predicted SEED Role

"Flp pilus assembly protein TadB" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (332 amino acids)

>GFF2207 Flp pilus assembly protein TadB (Variovorax sp. SCN45)
VREALLIVACIALLMAAAGLMLWQWARNRQVRLATERHLSQQILATSTATTAIPMPVRDR
ELPGEGMSSTLTTDPWLDTSPPTTEATRTGLLERAMPGWLVGVVEPRTIALALAAVVAIS
ILTGVLAGWLAAASILFVLLLAGSFLLWWRLQKFRRKLVSQLPAYIDAMVRLITIGNSTQ
AAFQLAIATTEAPLRVHLERSAALVRAGLDLDRALHQTATNVRIEEMFLLASILGLGVRY
GGRADLLLERVGNFMRDREQAEQELNAMSAETRLSAWILGLLPIGVGGFLILTNPGYFMG
MWNDETGRILIYSSATLQVVGVALLYRLARLA