Protein Info for GFF2192 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Cys regulon transcriptional activator CysB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 317 PF00126: HTH_1" amino acids 6 to 65 (60 residues), 79.3 bits, see alignment E=1.7e-26 PF03466: LysR_substrate" amino acids 91 to 294 (204 residues), 177.9 bits, see alignment E=1.8e-56

Best Hits

Swiss-Prot: 48% identical to RBCR_ALLVI: RuBisCO operon transcriptional regulator (rbcR) from Allochromatium vinosum

KEGG orthology group: None (inferred from 71% identity to mpt:Mpe_A1477)

Predicted SEED Role

"Cys regulon transcriptional activator CysB" in subsystem Cysteine Biosynthesis or DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (317 amino acids)

>GFF2192 Cys regulon transcriptional activator CysB (Hydrogenophaga sp. GW460-11-11-14-LB1)
MKNATFRQLRVFSEVARHLSFARAAQVLHLTPPAVTMQVKELEGHVGMPLFERNGRKVAL
TTVGEYMLVYARKVLATLKDAEDAAARLQKLETGTLVIGMVSTAKYFLPHLLAEFRREHG
SIDIRLAVSNREQLVKMLHANEVDIAIMGRPPKELATRAEPFAAHPHVFVAPVDHPLARA
GHVPAALLREYDFIVREQGSGTRAALEKFLADEHVELRVIMEMASNETIKQAVMAGMGLS
FLSLHTIGLELSNQLMTVLDVEGAPVVRAWNVVHTQSKLLSPAAEAFRYFVLERGEAYLA
ESFPAHFVGPDKSEAKN