Protein Info for GFF2191 in Variovorax sp. SCN45

Annotation: Pca operon transcriptional activator PcaQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 PF00126: HTH_1" amino acids 17 to 80 (64 residues), 63.4 bits, see alignment E=1.5e-21 PF03466: LysR_substrate" amino acids 106 to 312 (207 residues), 114.4 bits, see alignment E=5e-37

Best Hits

Swiss-Prot: 42% identical to YDCI_ECOLI: Uncharacterized HTH-type transcriptional regulator YdcI (ydcI) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 87% identity to vpe:Varpa_5170)

Predicted SEED Role

"Hypothetical Protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (333 amino acids)

>GFF2191 Pca operon transcriptional activator PcaQ (Variovorax sp. SCN45)
LKNPTDLRQDFVRNVQLRHLRCLVAVAQERHLARAAERLALSQPAVSKTLSELEAIVGTR
LVERSKAGRRGVQGLTAAGEQLLAHALRVLEALDASAQAVAPAAGGRIERLRIGALPSVA
PALLPQALARLRDGWPQVQIVVKSAANAALLDELRAGELDLVVGRMSDPRLMGGLSFELL
HTEPLVFAVRAGHPLALKAASVQAVLGYPLVVYGEGTIPRHNTESFLSARGLVLPTNALQ
TLDVAVARALVAVSDAVWITPLGAARGELADGRLVQLRIETAGTEEPVGLLQRSDAEPSA
LRAAMAVLLREAAREQGAVPPKARRKPRAGGSG