Protein Info for GFF2191 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868
Annotation: Beta-lactamase class C and other penicillin binding proteins
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to YFEW_SALTY: Putative D-alanyl-D-alanine carboxypeptidase (yfeW) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG orthology group: None (inferred from 99% identity to seg:SG2508)MetaCyc: 73% identical to penicillin binding protein 4B (Escherichia coli K-12 substr. MG1655)
Serine-type D-Ala-D-Ala carboxypeptidase. [EC: 3.4.16.4]
Predicted SEED Role
"Beta-lactamase class C and other penicillin binding proteins" in subsystem Beta-lactamase
MetaCyc Pathways
- peptidoglycan biosynthesis II (staphylococci) (12/17 steps found)
- peptidoglycan biosynthesis IV (Enterococcus faecium) (12/17 steps found)
- peptidoglycan maturation (meso-diaminopimelate containing) (6/12 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.4.16.4
Use Curated BLAST to search for 3.4.16.4
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (432 amino acids)
>GFF2191 Beta-lactamase class C and other penicillin binding proteins (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868) MKFTLVATVLLTFSLSAFAVEYPVLTTASPDQVGFDSQKLHRLDGWIQNQIDAGYPSINL LVIKDNHIVLQKAWGYAKKYDGSTLLAHPIRATTNTMYDLASNTKMYATNFALQKLVYEG KIDVNDLVSKYIPGFKDMPGDKIKGKNKLRIIDILHHVAGFPADPQYPNKNVAGKLFSQS KSTTLEMIKKTPLEYQPGSKHIYSDVDYMILGFIIESITAMPLDRYVETTIYKPLGLKHT VFNPLMKGFTPPQIAATELHGNTRDGVIHFPNIRTNTLWGQVHDEKAWYSMGGVSGHAGL FSDTHDMAVLMQVMLNGGGYGNVKLFDDKTVAQFTRRSPEDATFGLGWRVNGNASMTPTF GVLASPQTYGHTGWTGTLTSIDPVNHMAIVILGNRPHSPVANPKVNPNVFVSGLLPAATY GWIVDQIYGSLK