Protein Info for GFF219 in Xanthobacter sp. DMC5

Annotation: Protein phosphotransferase ChpT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 217 PF10090: HPTransfase" amino acids 89 to 210 (122 residues), 125.4 bits, see alignment E=5.6e-41

Best Hits

Swiss-Prot: 50% identical to CHPT_BRUA2: Protein phosphotransferase ChpT (chpT) from Brucella abortus (strain 2308)

KEGG orthology group: K13588, histidine phosphotransferase ChpT (inferred from 82% identity to xau:Xaut_3487)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (217 amino acids)

>GFF219 Protein phosphotransferase ChpT (Xanthobacter sp. DMC5)
MSADAPRIPLAVSALDLGALLCSRVCHDVISPVGAIVNGLEVLEDENAADMRDVALDLIA
KSARQASARLQFTRLAFGAAGSAGARLDTGDAEQVVRGVIEDQRTSLEWTLPRVLLPKNR
VKLLLNLVLLAGTTVPRGGVIRVTGAGEGDDVTFALVSTGQSARIPQGIEALAKGTLPEG
GLDAHSVQPFYAGLLARDCSLSIGFTQDGDTVTLTAA