Protein Info for GFF2154 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: possible transcriptional regulator, TetR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 220 PF00440: TetR_N" amino acids 20 to 61 (42 residues), 33.6 bits, see alignment 1.3e-12

Best Hits

KEGG orthology group: None (inferred from 68% identity to mpt:Mpe_A0175)

Predicted SEED Role

"possible transcriptional regulator, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (220 amino acids)

>GFF2154 possible transcriptional regulator, TetR family (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSKAPPRNDKFNERRAELGEAALQTLADLGYARTSLREIAQNSAFSHGVLHYYFTDKLDL
ILCSVRQYKARCVTRYDEVTTTSTEFGQLLDGFAEALGETLRTETTMHRLWYDLRSQALF
EAALRDDVEAIDKSLEKMIWRVMQRLSDLAGAPVKVPSEVAYALLDGLFQQALLKHLSGD
KKAIATMQAGVRLVLLQMVDAPAPPRARKAAPRRKLAAAA