Protein Info for GFF2154 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: L(+)-tartrate dehydratase beta subunit (EC 4.2.1.32)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF05683: Fumerase_C
  • amino acids 6 to 181 (176 residues), 131.7 bits, E=1.2e-42
• TIGR00723: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type
  • amino acids 13 to 181 (169 residues), 218.8 bits, E=2.3e-69

Best Hits

Swiss-Prot: 70% identical to TTDB_ECOL5: L(+)-tartrate dehydratase subunit beta (ttdB) from Escherichia coli O6:K15:H31 (strain 536 / UPEC)

KEGG orthology group: K03780, L(+)-tartrate dehydratase beta subunit [EC: 4.2.1.32] (inferred from 100% identity to set:SEN3187)

MetaCyc: 70% identical to L(+)-tartrate dehydratase subunit beta (Escherichia coli K-12 substr. MG1655)
L(+)-tartrate dehydratase. [EC: 4.2.1.32]

Predicted SEED Role

"L(+)-tartrate dehydratase beta subunit (EC 4.2.1.32)" (EC 4.2.1.32)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism

Isozymes

Compare fitness of predicted isozymes for: 4.2.1.32

Use Curated BLAST to search for 4.2.1.32

Protein Sequence (205 amino acids)

>GFF2154 L(+)-tartrate dehydratase beta subunit (EC 4.2.1.32) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MTKKILTTPIKDEDLADIKAGDIIYLNGHIVTCRDVAHRRLIEGGRELPVDVRGGAILHA
GPIVRPIKGEDDKFEMVSVGPTTSMRMEKFEKEFIAQTGVKLIVGKGGMGKGTEEGCAEH
KALHCVFPAGCAVVAAVCVEEIEDAQWRDLGMPETLWVCRVKEFGPLIVSIDTHGNNLFE
QNKIIFNQRKEIVADEICQNVSFIK