Protein Info for GFF2141 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: LysR family transcriptional regulator QseA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 PF00126: HTH_1" amino acids 2 to 57 (56 residues), 68.8 bits, see alignment E=3.1e-23 PF03466: LysR_substrate" amino acids 83 to 285 (203 residues), 134.5 bits, see alignment E=3.6e-43

Best Hits

Swiss-Prot: 95% identical to AAER_ECOL6: HTH-type transcriptional activator AaeR (aaeR) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 100% identity to sei:SPC_3437)

Predicted SEED Role

"LysR family transcriptional regulator QseA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (303 amino acids)

>GFF2141 LysR family transcriptional regulator QseA (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MSVFAKVVEFGSFTAAARQLQMSVSSISQTVAKLEDELQVKLLNRSTRSIGLTEAGKIYY
QGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKLLKEYPGLAVNLV
TGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKPYLAQYGVPEKPADLSS
HSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGTGIAYVPLMWVID
EINRGDLEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINALTDYFVDVAHLFQGMHGRG
KEK