Protein Info for GFF213 in Sphingobium sp. HT1-2

Annotation: Uncharacterized protein PA4513

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 845 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 144 to 163 (20 residues), see Phobius details amino acids 189 to 212 (24 residues), see Phobius details amino acids 342 to 363 (22 residues), see Phobius details PF03929: PepSY_TM" amino acids 7 to 365 (359 residues), 206.3 bits, see alignment E=1.9e-64 PF00258: Flavodoxin_1" amino acids 394 to 522 (129 residues), 78.9 bits, see alignment E=9e-26 PF00175: NAD_binding_1" amino acids 714 to 819 (106 residues), 25.7 bits, see alignment E=3.1e-09

Best Hits

Predicted SEED Role

"Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (845 amino acids)

>GFF213 Uncharacterized protein PA4513 (Sphingobium sp. HT1-2)
VTKRILFQIHWFLGITAGLVLALMGVTGATMSFEDEISEALSPRLYAPGVPSKPDLSPDQ
LIARVQADHPGYYIARLDWEMARHRSHSVRLSSSEGRGRKQGQVDRATGAWLGAPAGEGF
FHLMDDLHRWLALPGGGNGIGRQITAFSAIALIFFALSGLYLRWPRQALDWRAWLVLDLR
KTGRNLWRALHVVIGTWVLLFYLLSALTGLWWSYDWYRQGVIYSLTGKAPGEEGRRPEKR
DGIAPRPSIDPAWTAFRRATGNDYIWVRITQPAPSQPMKTISFDARPDGARHLRQTDKYS
YDPASYALEKRDLYDRRPLGVIITQSVYELHRGAFFGLPGRIIMMLTSLTMPLFTVTGFL
LYLSRRKRKQAARALAGDVAAVAGGDMGGGDLLIAYASQTGTAEIRARNAAQALAHGGVR
AQVVPVGRLTRDMLAGAQRILFVVSTYGEGEPPDMARGFASRLLRGGAIDLGHLHYGVLA
IGDREYPDFCAFGIAVDGWMAGAGAQPLFPLIAMGHDDEAAEQAWHDALHDLGAGEGDRG
QMVIPFTPWRLVARHALNPDSPALTAYYLQFEPVGTDVPEWQAGDIVELHPCNAPEAVEA
LLASQAPEGDLIAVPAALRAELARAMLPEAGTPLTMAEARALRPLPAREYSAASIMADGV
LDLVVRQVRDDDGRLGIGSGWLTAHMAPGETTMMRVRPNPGFRTDPAARGAMILIGNGTG
IAGLRAHLRAAAHDGIGGHWLLFGERSRAHERYFDAELSAWLADGTLARLDRSFSRDADC
GRYVQHLLADAGAELRERIGQGATILVCGSLEGMAQSVHEALIAILGEATLNDLAEAGRY
KRDVY