Protein Info for PS417_10850 in Pseudomonas simiae WCS417

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 353 transmembrane" amino acids 12 to 38 (27 residues), see Phobius details amino acids 58 to 77 (20 residues), see Phobius details PF00672: HAMP" amino acids 79 to 131 (53 residues), 29.9 bits, see alignment 8.9e-11 PF00512: HisKA" amino acids 140 to 192 (53 residues), 33.3 bits, see alignment 6e-12 PF02518: HATPase_c" amino acids 245 to 351 (107 residues), 85.3 bits, see alignment E=6.3e-28

Best Hits

KEGG orthology group: None (inferred from 75% identity to pfs:PFLU3075)

Predicted SEED Role

"Sensor protein baeS (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UAH0 at UniProt or InterPro

Protein Sequence (353 amino acids)

>PS417_10850 histidine kinase (Pseudomonas simiae WCS417)
MKLFNGLSRQIILSMSVVVLCVVALAVIGSYVFYALLWTYWPLPDEQVDEWMPANAEWAW
MGLTTCVSLAVGAFVATKLSRRILMPLNSVAENLRKLADGDLDVQAVAGDESIGEAAILV
NDFNSMAQRLKRMAQEQAFWNAAIAHELRTPLTILRGRLQGLAEGVFEPDTAQFYSLLGQ
VEGLARMIEDLRVVGLGDSGYLEVNVQDADLAAGVEDDVRLFEPSLAAAGFTLQLDLQRR
TLRCDPARIRQALLALLDNVRRHATPGNVNVHLSTRDGVHYLRVRDDGPGIDEDFATHLF
EAFQRGENSRSRAQGGSGLGLAVVRAIAIAHGGAVTCRKMENGGTLFELSWNL