Protein Info for GFF2067 in Xanthobacter sp. DMC5

Annotation: HTH-type transcriptional regulator DegA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 PF13407: Peripla_BP_4" amino acids 89 to 305 (217 residues), 53.5 bits, see alignment E=5.4e-18 PF00532: Peripla_BP_1" amino acids 95 to 332 (238 residues), 86.5 bits, see alignment E=4.6e-28 PF13377: Peripla_BP_3" amino acids 193 to 354 (162 residues), 121 bits, see alignment E=1.2e-38

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 87% identity to xau:Xaut_1177)

Predicted SEED Role

"Transcriptional regulator, LacI family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (365 amino acids)

>GFF2067 HTH-type transcriptional regulator DegA (Xanthobacter sp. DMC5)
MDETIPPPPGAAHPGASPAGAPIGKVTLQGLARELGLSTATISLALRDSPMVAEATRLKV
QEAARARGYVANRGAAALRTARTNIVALGLHDIVNPSFTELLAAVEDALSEAGKTVLLGV
SQEDVARQTRTLGTLAEYRPDAFLVSPAAHSRVEDLKALASTGIAVVQVTREIEGSGFDF
AGSDDVTGVALGVAHLVALGHRRIGMIGGFGAISTGRKRFAGYKAGLAAAGIPLDPTLVM
EGPGLRAEGRKAMARLLALDEPPTAAVCFNDLSAFGALMELQAAGLTAGRDFSLVGYDDI
EEARVWHPPLTTVHTFIPEYGRAAATLALKRIADPGRPVERAVMTPQLVVRASTCAPVPV
KRRPL