Protein Info for GFF2056 in Variovorax sp. SCN45

Annotation: Septum-associated rare lipoprotein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 236 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF03330: DPBB_1" amino acids 97 to 184 (88 residues), 83.4 bits, see alignment E=5.6e-28 TIGR00413: rare lipoprotein A" amino acids 99 to 191 (93 residues), 139.5 bits, see alignment E=7.4e-45

Best Hits

KEGG orthology group: K03642, rare lipoprotein A (inferred from 78% identity to vpe:Varpa_5309)

Predicted SEED Role

"Rare lipoprotein A precursor" in subsystem Peptidoglycan Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (236 amino acids)

>GFF2056 Septum-associated rare lipoprotein A (Variovorax sp. SCN45)
LRGRAAGATVAASLRGALHAALVAATCALVGCAMPPATDAEGGGNLKPLPRALAVPPGAA
ARSSVPSVRYDLAVSGTGELTPDDGVPDDGPREIFERGGASWYGIQFHQRKTASGERFDM
TAMTAAHKTLPFNTRVCVRSLVNGSEVLVRINDRGPYSLGRVIDLSRAAADRIGLTGLGI
KQVALTVVDHDGMRCGGLPVEPGDAQAPVASAEPQQRAQVKVPARRKVIVPQRRRK