Protein Info for GFF2052 in Xanthobacter sp. DMC5

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 839 transmembrane" amino acids 21 to 48 (28 residues), see Phobius details amino acids 68 to 86 (19 residues), see Phobius details PF13188: PAS_8" amino acids 232 to 284 (53 residues), 14.7 bits, see alignment 7.2e-06 PF12860: PAS_7" amino acids 351 to 463 (113 residues), 41.8 bits, see alignment E=3.4e-14 amino acids 479 to 590 (112 residues), 54.8 bits, see alignment E=2.9e-18 PF00512: HisKA" amino acids 607 to 674 (68 residues), 63.8 bits, see alignment E=3.6e-21 PF02518: HATPase_c" amino acids 721 to 830 (110 residues), 83 bits, see alignment E=6.5e-27

Best Hits

Predicted SEED Role

"FIG056333: sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (839 amino acids)

>GFF2052 Sensor histidine kinase RcsC (Xanthobacter sp. DMC5)
MAERIRRSGARRPARGRRQGPAPATGCANFCVGTRTVLFGGFLLATTALAGTPASADGWT
IAMSAAEALWPVIALSACAVAGLVALRSRRVAADLGARMDKAEAEARDAGAAAARARAEA
HAARILLTAGAPAFMAWSGRTLPVDVHGATPEAFRASLGAASVALDQALEQLRREDGTVS
QLVETPAGPARLEGRSLGGAGVLLLRPADAAEVSAKAEAADFAEAERMAHGLAAALDAAA
APAWLRRPDGTLVYVNPAFATAVGAPSAAEARGAGLDLLDARIRSAALTAEGTAGTFRQR
VKAVASGQRRQMDVVEVAGPFGTAGIAIDVTGEDVAKAETARTVAAHQRTLDQLTTAVAI
FGADERLVFHNAAYERLFDLAPGLLDQRPPENEILEDLRRRRKVPEQADFRAWRAQLREA
YRAIEPVNDWWHLPGGQMLRVVITPNAEGGITYLFDDLSEHLALESRYNSLIRIQGETLD
GLAEAVAVFGADGRLNLYNQAFLALWSLDAQAMGDKPHVDAVAAMCRPLYGETAAFSRIR
QAVTAIGPRDATTLRIERPDGRVLDGATQPLPDGGTMVTFRDVTDSVKVERALTERAEAL
EAADKLKNAFVGHVSYHLRTPLNTLMGYADMLREGLAGPLNDRQRDYLDHMRQSSDLLRA
LIDDILDLATIDAGAMELDLAEVDVRELVLSVAEAVRDSVDEARLSLAVNIDPAAGVFVA
DARRLRQILFNLLSNAIAVSPEGGTVTLGAIRRDGALVFTVRDEGPGVPAEVKETLFDRF
ESRSAGPRHRGVGLGLAIVRSFVSLHGGSVTVGPASATRGTLATCIFPLDGERRREAAE