Protein Info for GFF2049 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Permeases of the major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 55 to 77 (23 residues), see Phobius details amino acids 88 to 111 (24 residues), see Phobius details amino acids 118 to 138 (21 residues), see Phobius details amino acids 148 to 172 (25 residues), see Phobius details amino acids 184 to 203 (20 residues), see Phobius details amino acids 231 to 255 (25 residues), see Phobius details amino acids 265 to 284 (20 residues), see Phobius details amino acids 296 to 318 (23 residues), see Phobius details amino acids 323 to 341 (19 residues), see Phobius details amino acids 352 to 376 (25 residues), see Phobius details amino acids 382 to 401 (20 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 331 (302 residues), 64 bits, see alignment E=1.2e-21 PF06779: MFS_4" amino acids 31 to 399 (369 residues), 189.2 bits, see alignment E=1.5e-59

Best Hits

KEGG orthology group: None (inferred from 68% identity to vpe:Varpa_3157)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (406 amino acids)

>GFF2049 Permeases of the major facilitator superfamily (Hydrogenophaga sp. GW460-11-11-14-LB1)
MNPRTEPASLTDVPDTTPYVRLALALSLGAAVSLGITRFAYGLLLPPMREDLGWSYTLAG
AMNTFNALGYLIGALATPWLMRRFSPTGLLLAGSLLASLFMGLSGFFTAAAPLLAQRLLA
GVASALVFIAGGLLAARLGARQPGRSGFLLGLYYGGTGLGIVVSALGVPPVLAAAVSQPH
GWAWAWWGLALVCLLATALMVWPARVLAVHAAPAAGAQAGHGRVFRVRDFAFSLAGYAGF
GVGYIGYMTFVIALLREQGSSSGAITLFYALLGAAVVASSRIWAGLLDRHRDGQALARLN
ALLGVAAIVPALTGSWLLVLASGLVFGGVFLSVVASTTALVRHNLPPAQWAAGISAFTIV
FAAGQIVGPTVVGFIADGPGGLARGLVFSAVALWLGAALAWRQRAL