Protein Info for GFF2038 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: LysR family transcriptional regulator YfeR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 PF00126: HTH_1" amino acids 5 to 64 (60 residues), 81.7 bits, see alignment E=3e-27 PF03466: LysR_substrate" amino acids 90 to 293 (204 residues), 151.1 bits, see alignment E=2.9e-48

Best Hits

Swiss-Prot: 79% identical to YFER_SHIFL: Uncharacterized HTH-type transcriptional regulator YfeR (yfeR) from Shigella flexneri

KEGG orthology group: None (inferred from 99% identity to sew:SeSA_A2659)

Predicted SEED Role

"LysR family transcriptional regulator YfeR" in subsystem DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (308 amino acids)

>GFF2038 LysR family transcriptional regulator YfeR (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MNYSLRQLRIFITVAQAKSFSRAGDRIGLSQSAVSHSVKELERQTGVRLLDRTTREVVLT
EAGQQLATRLERVLDELNSILRDAGRVGTQLTGTVRVAASQTISAHLIPQCIAQSNSLYP
AIDFVLHDRPQQWVLESIRQGEVDFGIVIDPGAAVDLQCEAILSEPFLLLCRQDHPLAHQ
EWVSWQDLKQASLVLQDYASGSRPLIDAALAHFAIEADIVQEIGHPATLFPMVEAGIGIS
VLPALALPLPQGSHLQVKRLTPVVERQLMLARRKNRSLSTAAQALWDVVRTQASELTAAR
AKDPLYQL