Protein Info for GFF2019 in Sphingobium sp. HT1-2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 44 to 66 (23 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 132 to 153 (22 residues), see Phobius details PF01545: Cation_efflux" amino acids 18 to 181 (164 residues), 47 bits, see alignment E=1.3e-16

Best Hits

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (253 amino acids)

>GFF2019 hypothetical protein (Sphingobium sp. HT1-2)
MKTAWIEDTLGLVPPVMFLIAAHMERHAHRSRRFPFGFERVNGLGFFVAAVALTAVGALL
LYNALIALGSAEHASVGSIVILGQDIWLGWLMIAAQIYSLIPPLFIGRKELPLAQALNDK
LLHTDALMNKANWLTGAAGLAGIIGLGLGWWWADSVAAAIISLDVLNDGIKALRSSTAEL
VDGAPRALSSTDLSEDAQSLCDRLKAEFPGATIRLRETGRLIRAEVHDTHPPAQCRHPRY
CWPEGEDRAWRLA