Protein Info for GFF1978 in Sphingobium sp. HT1-2

Annotation: Flp pilus assembly protein RcpC/CpaB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details TIGR03177: Flp pilus assembly protein CpaB" amino acids 6 to 252 (247 residues), 197.2 bits, see alignment E=1.5e-62 PF08666: SAF" amino acids 49 to 109 (61 residues), 34.1 bits, see alignment E=3.3e-12 PF16976: RcpC" amino acids 119 to 231 (113 residues), 109 bits, see alignment E=1.3e-35

Best Hits

KEGG orthology group: K02279, pilus assembly protein CpaB (inferred from 81% identity to sjp:SJA_C1-24460)

Predicted SEED Role

"Flp pilus assembly protein RcpC/CpaB" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (337 amino acids)

>GFF1978 Flp pilus assembly protein RcpC/CpaB (Sphingobium sp. HT1-2)
MDAKKIVLLVGALIIAVTTALLARSMLSSSSTPQVNAAAMPNEADQPHVLVATKALPVGT
ILDAESFRFQPWPKDLIEAAYYLKGQADPLKLAGSVVRNAITAGQPLTQGAVIRPGDRGF
LAAALGPGMRAVTVPVSAQNAVAGFVFPGDRIDLVLTQTVSGGGDGAPLKVSETILRNLR
VLATDQRTDAMGPDGKPVVQTYSNVTVEVTPKIAEKLAVSQTIGSLSLSLRSIADTASDL
DAAIAGSDVDLPDGTNPGSEKSIIAKIAARPVDRGSTYSTGADVSRYQRSSVPAKPDAGM
PAMAAPGGAPVGTAVFKGPTVRIARGTNVTEVPVGGK