Protein Info for GFF1972 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 TIGR03298: transcriptional regulator, ArgP family" amino acids 4 to 298 (295 residues), 352.3 bits, see alignment E=9.1e-110 PF00126: HTH_1" amino acids 7 to 64 (58 residues), 67.6 bits, see alignment E=7.7e-23 PF03466: LysR_substrate" amino acids 97 to 279 (183 residues), 52.2 bits, see alignment E=5.5e-18

Best Hits

KEGG orthology group: K05596, LysR family transcriptional regulator, chromosome initiation inhibitor (inferred from 75% identity to pna:Pnap_0095)

Predicted SEED Role

"Transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (309 amino acids)

>GFF1972 Transcriptional regulator (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSTFDPDALECLAAIIEEGGFERAAQRLSITQSAVSQRLRALEAQVGTVLIVRSRPLKPT
AAGQLMLKHAKMMRLLRADLEKDLKELAPSSTGNGRDDERISVAINADSIATWALPALDA
LAQGGLPIEIITDDQEFTHEWLREGQVLGCVTSLGQALRGCKMEALGTMDYVVVAQAAYA
AEHLPKGLNAHNFHKVPFVAFNRKDNLQHGFVSHAFGLSRVMLKQLFVPSSEGQVRAVLA
GWGVSVVPELRVRELLARGELVNLAPRHRLGVALHWHCWNLNSDVLDALSMALRRAAALN
LRGVEAVAA