Protein Info for GFF1957 in Methylophilus sp. DMC18

Annotation: Riboflavin transporter RibZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 472 transmembrane" amino acids 23 to 44 (22 residues), see Phobius details amino acids 63 to 83 (21 residues), see Phobius details amino acids 91 to 110 (20 residues), see Phobius details amino acids 116 to 140 (25 residues), see Phobius details amino acids 150 to 171 (22 residues), see Phobius details amino acids 177 to 198 (22 residues), see Phobius details amino acids 210 to 230 (21 residues), see Phobius details amino acids 238 to 257 (20 residues), see Phobius details amino acids 278 to 302 (25 residues), see Phobius details amino acids 314 to 332 (19 residues), see Phobius details amino acids 344 to 362 (19 residues), see Phobius details amino acids 368 to 391 (24 residues), see Phobius details amino acids 408 to 428 (21 residues), see Phobius details amino acids 446 to 467 (22 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 27 to 434 (408 residues), 240 bits, see alignment E=2.4e-75 PF07690: MFS_1" amino acids 31 to 420 (390 residues), 178.6 bits, see alignment E=8.9e-57

Best Hits

KEGG orthology group: None (inferred from 67% identity to dar:Daro_1015)

Predicted SEED Role

"Multidrug resistance protein B"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (472 amino acids)

>GFF1957 Riboflavin transporter RibZ (Methylophilus sp. DMC18)
MSLHLLPHSFEALSLRYGERYKWMVLLIIGVGTMAGVLCTSSFNVAVPALTRTFHLGQDH
VQWAMTAFLAAMTIGMLPAAWWLQRFGLRRVFMWTLWLLVAASVAGFYAHSFVQVVIARL
LQGLAAGVLQPLGVMALMRLFPPDIQGRASGILIVGIAFTPAIAPSISGWLLDQFGWQAI
FLLGVPFALIALLCAWRWLPAPRQQPVNAFDWAGLGWLSAATIGLIEFVSSLHHSGLFAP
WTWGQALLTVGSLLCYMRHARQLPHAIIQLHLFQRPTFSRGTLVAFAYGFGLYASTYLIP
VFLQNAMAFSATEAGVLLLPSGIALVLTIPIAGRMADQLSPRRITLAGLVIFGASFIVFA
VAADQVRYWEIVAATIVGRIGLGLILPALNLATLHEMEPQHLGQSSVVVSYARQLGGVVG
VAMMAVFMEWRERIYGQLPPGIFEAYAQGFLLLSAVIVLAIMVALGMQDRKR