Protein Info for GFF1948 in Sphingobium sp. HT1-2

Annotation: Peptidoglycan glycosyltransferase FtsW (EC 2.4.1.129)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 transmembrane" amino acids 41 to 64 (24 residues), see Phobius details amino acids 80 to 101 (22 residues), see Phobius details amino acids 109 to 129 (21 residues), see Phobius details amino acids 150 to 165 (16 residues), see Phobius details amino acids 172 to 189 (18 residues), see Phobius details amino acids 195 to 212 (18 residues), see Phobius details amino acids 218 to 237 (20 residues), see Phobius details amino acids 303 to 324 (22 residues), see Phobius details amino acids 334 to 355 (22 residues), see Phobius details amino acids 369 to 390 (22 residues), see Phobius details PF01098: FTSW_RODA_SPOVE" amino acids 42 to 392 (351 residues), 242.1 bits, see alignment E=4.7e-76

Best Hits

KEGG orthology group: K03588, cell division protein FtsW (inferred from 88% identity to sch:Sphch_1424)

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (408 amino acids)

>GFF1948 Peptidoglycan glycosyltransferase FtsW (EC 2.4.1.129) (Sphingobium sp. HT1-2)
MDSEGRKGMFRAGELVKGFKTRTVPRERTALAIWFWEIDRVLLSLIVALMAIGLVAVAAA
SPVAAIDRSTAQVAVNPLIYFYRQLMWVFIGLPIMLVISMLPRPQARRLAIFLAVFFFLM
LLFVPLLGSTVNGAKRWIDLPGFRFQPSEFLKPVYVVTLAWLLSLRAKDQSLPVMPLTGA
MTLLIAAILMKQPDFGQTVIFLACWGVLLMLSGLEMRWIAMLGGLALAGLVAVYMFYENG
RQRINDFLGIGVQMDTGPDQTDLAFRTITHGGFTGVGPGGGQNKFRLPEAHTDYIFSVIG
EEFGLLACIAIACVYLAIVVRVLLRLLDEEDNFTILAAAGLTTQFGLQAIINMGVNAQIF
PSKGMTLPFISYGGSSMLALCIGVGLLLAFTRRNPFMGRHTVVKWSGR