Protein Info for GFF1934 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Rubredoxin-NAD(+) reductase (EC 1.18.1.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 407 PF00301: Rubredoxin" amino acids 10 to 55 (46 residues), 71.2 bits, see alignment 1.8e-23 PF07992: Pyr_redox_2" amino acids 84 to 363 (280 residues), 132 bits, see alignment E=9.3e-42 PF02737: 3HCDH_N" amino acids 224 to 313 (90 residues), 23 bits, see alignment E=2e-08 PF00070: Pyr_redox" amino acids 224 to 291 (68 residues), 26.1 bits, see alignment E=3e-09

Best Hits

KEGG orthology group: K05297, rubredoxin-NAD+ reductase [EC: 1.18.1.1] (inferred from 54% identity to mpo:Mpop_4666)

Predicted SEED Role

"Rubredoxin-NAD(+) reductase (EC 1.18.1.1)" in subsystem Rubrerythrin (EC 1.18.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.18.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (407 amino acids)

>GFF1934 Rubredoxin-NAD(+) reductase (EC 1.18.1.1) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTALAPYQSYICDACGYLYNEADGDPDGGLPPGTRYADIPDDWACPLCGVTKADFRPYTP
PSLDALRAAVAHRAPMAARGAAGVVIVGAGRAGWQVAEALRALDTDLPLTLVSDCAGDLY
DKPLLSVALARGLAPGALTKESGPTAAARLNVRLLAHTQAVRICPDTRTLRTTRGNLRYD
RLVLAHGAQAALPPALPAALCWRINHLGAYKRLRAALGDSPKDVAIVGAGLIGSELANDL
ALGGHRITLLDVQAAPLARWPAEHAGTPLLEAWKDLAIRFVGSVQVAQLERVAGRYRLST
ACGQRFAADQVIAAAGLQTPPRLAHSAGLAWDNGIAVDAATLRTSDPRIHALGDCIAVNG
QASRYIEPIARQARAIAAGICGAAPAPYELRAAVVRVKTTSRPLTLH