Protein Info for GFF193 in Methylophilus sp. DMC18

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 510 transmembrane" amino acids 21 to 59 (39 residues), see Phobius details amino acids 65 to 82 (18 residues), see Phobius details amino acids 88 to 106 (19 residues), see Phobius details amino acids 118 to 136 (19 residues), see Phobius details amino acids 154 to 173 (20 residues), see Phobius details amino acids 180 to 199 (20 residues), see Phobius details amino acids 229 to 253 (25 residues), see Phobius details amino acids 274 to 295 (22 residues), see Phobius details amino acids 301 to 321 (21 residues), see Phobius details amino acids 327 to 345 (19 residues), see Phobius details amino acids 363 to 392 (30 residues), see Phobius details PF00916: Sulfate_transp" amino acids 14 to 363 (350 residues), 169.1 bits, see alignment E=2e-53 PF01740: STAS" amino acids 407 to 489 (83 residues), 32.9 bits, see alignment E=6.9e-12 PF13466: STAS_2" amino acids 415 to 486 (72 residues), 29.6 bits, see alignment E=9.5e-11

Best Hits

KEGG orthology group: None (inferred from 73% identity to mfa:Mfla_0005)

Predicted SEED Role

"Sulfate permease" in subsystem Cysteine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (510 amino acids)

>GFF193 hypothetical protein (Methylophilus sp. DMC18)
MFADQSSLKFSEIKTNVLSGLTVALAMVPEAIAFALIAHVSPLTGLYAAVLVSLITSVFG
GRPGMISGAAGALAVVMVALVVQYGVQYLFATIILMGLLQILFAVAKLGKFIRMVPHPVM
LGFVNGLAIVIFLAQFNHFKTIQADGSYGWMSGAPLYIMLGLIAITMAIIYLLPRLTRAI
PSTLAAIIVVSTSVIYLGLDTKTVGDLGSIAGGLPTFHFPEVPWTLETLYIIFPYALILA
AVGLIETLLTLNLIDEMTETRGRPNREAMAQGMANVVTAFFGGMGGCAMIGQSMININNG
ALKRLSGIATSLFLLSFILFASRWIEMIPLAALIGVMFVVAEKTFEWGTLNLFGKVPKQD
VFVGLLVGGVTIIADLAIAVIAGVIVSALVFAWEHAKQLKVYTEKDKNGMTVHQLHGTLF
FASIANFQALFNPASDDAQVVIDFKHAKVMDHSALMAIDSLAAKYRAVGKSLHLRHLSPD
CQELLESAKAIIEVNLLEDPTYRVSDDKLA