Protein Info for PS417_09815 in Pseudomonas simiae WCS417

Annotation: DNA mismatch repair protein MutT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 PF12535: Nudix_N" amino acids 4 to 57 (54 residues), 63.1 bits, see alignment E=1.6e-21 PF00293: NUDIX" amino acids 73 to 180 (108 residues), 44.6 bits, see alignment E=1.5e-15

Best Hits

Swiss-Prot: 40% identical to YJHB_BACSU: Putative ADP-ribose pyrophosphatase YjhB (yjhB) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 96% identity to pfs:PFLU2112)

Predicted SEED Role

"possible MutT-like domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U211 at UniProt or InterPro

Protein Sequence (207 amino acids)

>PS417_09815 DNA mismatch repair protein MutT (Pseudomonas simiae WCS417)
MENTWLAQAKRLQALASTGLHFCTDDFERERLEEIAEIAHSMLAQLGNVPLERITGLVTD
FAQRYSTPMIDVRGAVIQDDRILLVRELTDGCWALPGGYADIGLSAAENIVKEIREEAGL
TVTARALYSVTHKAKGLYRPDVRDFYKLYFLCEPVDQSAPMAGFETTEVGFFRLNDLPPL
SRGRTIESDLEAAFAFHRGEITQTLFD