Protein Info for PS417_09795 in Pseudomonas simiae WCS417

Annotation: lipase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 716 transmembrane" amino acids 478 to 494 (17 residues), see Phobius details PF01764: Lipase_3" amino acids 339 to 464 (126 residues), 85.8 bits, see alignment E=1.4e-28

Best Hits

KEGG orthology group: None (inferred from 84% identity to pfs:PFLU2108)

Predicted SEED Role

"Lipase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See U1THV6 at UniProt or InterPro

Protein Sequence (716 amino acids)

>PS417_09795 lipase (Pseudomonas simiae WCS417)
MKQDAWKQSFFSDSKPACSLRGHWVSFCLVDELGVGAAYGGLPYTVHDSAGQEYKGRLNG
EGFAKLDNIFCGPVVLVLDDLYSGTEPPYLQLMLRPTYKLPITELQVRAEQTRFAASDGQ
RLDSNPAQHKANRFYQVEVRDLVRHVAHLPPVAQRSHQPLRHALNMMGELGFGPPQSNLV
GVVLFPNNHTALEVRPLRAFRPMLSTDDGFCALNLYQLALMATLSYCNFGQVPPEKPHDH
VRFPLDPSIGHLFAEELSGFHEAWRFDAEQVDRFFPLYEEVPYSQRFEILPFDPELYPQN
QPELQEKQEHPANVHFFDDEALGTDTQAFITHHDEVILIAVRGTASGADGMRDANAHQVP
YTEGVGKAHQGFYQAYRAVRDFVLHYLDQFHTGQRIIICGHSLGGAIALLLAEGLRRAPE
CNYNILLYTYGAPRAADSEFTQGASTLVHHRIVNHNDPVPSVPAPWMNTTAKLWIPGAVT
LFSAPAPGGLLFAAGLVRFGANPYQHHGEQHHFMPIMLPDGTQSSVLWKPGCESIQEAGC
NRTLQLRGDMPERDNLLRQLFQANQHFMTASYIPAAWATLRRWQQTQESNGPLVTPSEFE
LLDLALETMRQQLRNKRRELARLRSANDRGYEHNEALNTEIDRLHTSRERLATLRWRRLE
ARDVYGSQAHSANVQPSLKRWFSHRENREPSQVASIPPAQHHEWGRVQTLDIDSIV