Protein Info for GFF1912 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 490 transmembrane" amino acids 231 to 252 (22 residues), see Phobius details amino acids 272 to 296 (25 residues), see Phobius details amino acids 301 to 319 (19 residues), see Phobius details amino acids 326 to 346 (21 residues), see Phobius details amino acids 353 to 370 (18 residues), see Phobius details amino acids 400 to 419 (20 residues), see Phobius details amino acids 433 to 450 (18 residues), see Phobius details amino acids 471 to 489 (19 residues), see Phobius details PF12710: HAD" amino acids 18 to 161 (144 residues), 38.9 bits, see alignment E=1.3e-13 PF01040: UbiA" amino acids 221 to 389 (169 residues), 79.5 bits, see alignment E=2.5e-26

Best Hits

KEGG orthology group: None (inferred from 47% identity to har:HEAR3102)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (490 amino acids)

>GFF1912 integral membrane protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
LTPNTTPAPTDTCPLYVDLDGTLTHSDTLHESAMLFVRANPLNLLRMLTWLPLGKAGFKQ
RLASAVRPDPARLPYNEPFVQYLRDEHARGRPLVLASAADARIVQDVASHLAVFDDSLGT
NAQADGVNLSRGNKRAAIDAHARAHGHGSWAYAGNSRDDLDVWAGSAEAVAVNAPGGVVA
SLQRTHPQARVFEREPLRLKTVLRAIRLKQWSKNGLLFIPLLAAHSLDPALWGAVWLAFI
AFGLCASATYLVNDLLDLPNDRAHRIKRHRPLASGAIGITTAVGLGVAMLVLAFVLAFAV
STGFAVVLLAYTVTTLAYSMYLKRLALIDVLVLSGLYTLRIGAGAVASGVDLSNWLLAIS
IFLFLSLALVKRCAELEELEDDQRTLAPGRGYQPRDLASLRAMGMSSGFMAVLVLTLYID
SQNSQKLYAHADWLWAAAPVLLLWIMRIWLKTGRRELHGEDPLQFALKDPFSWVTLLVMG
GIGFVATVGF