Protein Info for GFF1895 in Xanthobacter sp. DMC5

Annotation: Protein GrpE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 215 PF01025: GrpE" amino acids 40 to 200 (161 residues), 174.4 bits, see alignment E=8e-56

Best Hits

Swiss-Prot: 53% identical to GRPE_AGRVS: Protein GrpE (grpE) from Agrobacterium vitis (strain S4 / ATCC BAA-846)

KEGG orthology group: K03687, molecular chaperone GrpE (inferred from 84% identity to xau:Xaut_2533)

Predicted SEED Role

"Heat shock protein GrpE" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (215 amino acids)

>GFF1895 Protein GrpE (Xanthobacter sp. DMC5)
MSEQKRAPETGGDASENGTAQGNAQVNEATAEAEATAMADAAIGDPAGDKARLEGEIASL
KDKFLRAFAEAENVRRRAEKEIQDAKTYGIASFARDVLNVADDLARALGSVEAEAKATAE
GGFKALLDGLELTERGLVKALEKHGIRKIEPKGEKFDPNLHQAMFEVPDPSVPTGTVVQV
VQAGYVIGERVLRPAMVGVARGGPKAEANKATGAA