Protein Info for GFF1885 in Variovorax sp. SCN45

Annotation: Gluconate transporter family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 460 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 37 to 55 (19 residues), see Phobius details amino acids 67 to 88 (22 residues), see Phobius details amino acids 112 to 140 (29 residues), see Phobius details amino acids 147 to 165 (19 residues), see Phobius details amino acids 172 to 194 (23 residues), see Phobius details amino acids 203 to 223 (21 residues), see Phobius details amino acids 243 to 263 (21 residues), see Phobius details amino acids 284 to 309 (26 residues), see Phobius details amino acids 316 to 333 (18 residues), see Phobius details amino acids 345 to 368 (24 residues), see Phobius details amino acids 374 to 392 (19 residues), see Phobius details amino acids 398 to 421 (24 residues), see Phobius details amino acids 436 to 459 (24 residues), see Phobius details PF02447: GntP_permease" amino acids 15 to 458 (444 residues), 440 bits, see alignment E=9.3e-136 TIGR00791: transporter, gluconate:H+ symporter (GntP) family" amino acids 15 to 459 (445 residues), 416.6 bits, see alignment E=6.7e-129 PF03600: CitMHS" amino acids 26 to 405 (380 residues), 33.3 bits, see alignment E=3e-12

Best Hits

KEGG orthology group: K03299, gluconate:H+ symporter, GntP family (inferred from 57% identity to rsa:RSal33209_2014)

Predicted SEED Role

"Gluconate transporter family protein" in subsystem D-gluconate and ketogluconates metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (460 amino acids)

>GFF1885 Gluconate transporter family protein (Variovorax sp. SCN45)
MNASTALNAHDIQVLAVAAVGIALLVVLIVWLKLHAFLALTIGALFVGVGSGIPLDKVTA
SYENGVGGVLGYVGVLIALGAMLGKLLADSGGADRLVETLLRGRPATLPWKMALVASIIG
IPMFFEIGLVLLIPVVMLAVHRSKGPAMKLGIPALAGLSVLHGFIPPHPGPLAAIAILHA
NVGVTLALGLLIAIPTVAVAGPLFGLLAARLVPIGAAGAGLAVTASGSSTGAGDQKPTGS
PTFAWTLITLLSPLVLMLLKAAADIWMDKTAALRPVLDFVGDPVFALLVAVLLAMVTFGT
AVGFTVPVLAKKIADSLLPVVGVMLIVGAGGGFKQALVDGGTGNAIAKIALAAGLSTLVL
GWIVAVLIRLATGSATVATVTAAGIIAPLAGGLSTNHLSLVVLAIGAGSLFFSHVNDAGF
WLVKEYFGLTVGQTIKTWSVMETVISVMGLLLTLALSAVF