Protein Info for GFF1869 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: AmpG permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 471 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 45 to 69 (25 residues), see Phobius details amino acids 119 to 137 (19 residues), see Phobius details amino acids 143 to 167 (25 residues), see Phobius details amino acids 187 to 204 (18 residues), see Phobius details amino acids 224 to 246 (23 residues), see Phobius details amino acids 285 to 305 (21 residues), see Phobius details amino acids 324 to 343 (20 residues), see Phobius details amino acids 350 to 369 (20 residues), see Phobius details amino acids 375 to 401 (27 residues), see Phobius details amino acids 412 to 431 (20 residues), see Phobius details amino acids 441 to 461 (21 residues), see Phobius details PF13347: MFS_2" amino acids 113 to 434 (322 residues), 32.3 bits, see alignment E=6.4e-12 PF07690: MFS_1" amino acids 297 to 467 (171 residues), 33.8 bits, see alignment E=2.9e-12

Best Hits

KEGG orthology group: K08218, MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG (inferred from 76% identity to vpe:Varpa_0269)

Predicted SEED Role

"AmpG permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (471 amino acids)

>GFF1869 AmpG permease (Hydrogenophaga sp. GW460-11-11-14-LB1)
VPAPFFLLSTSMSVPPTLPQAAPTDVDTTARPTWGETLRVYLEPASLRMFALGFSAGLPL
LLVLGTLSFRLREAGLDRTTIGYLSWVGLAYGFKWCWAPLVDRLPIPLLTRWLGRRRSWL
LLSQALIMASLVGMALADPRTELQLVVWFALAVAFASATQDIALDAFRIESADVRHQGAL
AATYQTGYRLAMIWAGAGVLWIAARAEIAPAAVAAAPGALYQQAAWTTAYLVMAASMLVG
VFTVLFSREPARVALPPAKNAADWLRGALIEPFADFLRRYGRQALLILALIGVYRISDVV
MGIMANPFYVDMGYTKDEVAAVTKVFGVIMTLVGAFIGGALSLRLGVMRVLMLGAVLSAA
SNLLFAWLAGHGHDVTALILVISADNLSAGVASAAFIAYLSGLTNVRYSATQYALFSSMM
LLAPKWLAGYSGAFVDAYDYPTFFIATACLGVPVLLLIWLATRLAPVEPKA