Protein Info for PS417_09435 in Pseudomonas simiae WCS417

Annotation: glyoxalase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 152 PF00903: Glyoxalase" amino acids 19 to 127 (109 residues), 53.7 bits, see alignment E=2.9e-18 PF18029: Glyoxalase_6" amino acids 20 to 126 (107 residues), 36 bits, see alignment E=9.3e-13

Best Hits

KEGG orthology group: K04750, PhnB protein (inferred from 76% identity to pfo:Pfl01_3921)

Predicted SEED Role

"PhnB protein; putative DNA binding 3-demethylubiquinone-9 3-methyltransferase domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UFM0 at UniProt or InterPro

Protein Sequence (152 amino acids)

>PS417_09435 glyoxalase (Pseudomonas simiae WCS417)
MSVKPIPEGYHSVTPYMGINNAAEAIAFYKKAFGATQVMRLDMPDGKVGHAELRIGDSAI
MLGTPCDEMALRNPDEHTSVGLHLYVKDVDAQFKQAVAAGAVVVSEPKDQFYGDRSASVK
DPFGHLWFLATHKEDLTEAQIRQRAMEMFKQA