Protein Info for GFF1851 in Variovorax sp. SCN45

Annotation: TOMM biosynthesis cyclodehydratase (protein C) / TOMM biosynthesis docking scaffold (protein D)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 745 TIGR03882: bacteriocin biosynthesis cyclodehydratase domain" amino acids 180 to 352 (173 residues), 68.6 bits, see alignment E=7.4e-23 TIGR00702: YcaO-type kinase domain" amino acids 392 to 621 (230 residues), 80.7 bits, see alignment E=1.1e-26 PF02624: YcaO" amino acids 394 to 707 (314 residues), 276.3 bits, see alignment E=2e-86

Best Hits

Predicted SEED Role

"SagD family docking scaffold"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (745 amino acids)

>GFF1851 TOMM biosynthesis cyclodehydratase (protein C) / TOMM biosynthesis docking scaffold (protein D) (Variovorax sp. SCN45)
MRDAAAPDLFGDVFQWHEKYLPPTVLRDRLLLLSENELLVLGSPGVMALERVLREGVSLA
TYCRDASAGALLAEMLHALGALLRQGLVRPVMLRGGEAYLLPDFSASHAPMAVSAHVDAI
SLTDAVGRGAALRWGQALAEEFDEAGDKVGDEAGLTIVFCDDYLDPRLGAIDARQRSKGR
PWLLVKPAGEQAMVGPLFTPRPVDAEGDAGHAHEAPACWHCLSHRWLRNRPARAWWRARH
GDLGSGPPVRAGASLVVERLDGLLAKARQMVAQRGDAQAVWTLDPLERNPVVARPQCPQC
GTPGLMALVQHGRIAPVPGGPVASADGGWRTAPASATVERLSRHVGPLCGVIARVKPLNA
ESEDMLTVYRSEIFKTPPPFGDPAPGAWTQVCLGKGMSAAQSRASAMCEAVERYSAFYQG
DEATVIAPAADLDAPCIAPTALARFSEHQKSQFDTEKPPHAVVSTDAQPQEPTWWAPAWS
LTADARRYLPLAFCHAHAPAESQYHVTWTSNGCAAGNTVEEAILQGFLELVERDAAAIWW
YGQVRRPAIDLDGMPVASRLRLSRTWGLQWAHWVLDITHDFGIPVVVAVGRHRQTGEWAI
GFGCSPDRMLACERALTEMSQLIAAGKTFPVPSAAGLEGPPAFLMPMEEGGTVPLRAAPD
PDAPRDIAGEIARCVGIAAGLGLETIVLDHSRPDIPLRTVKVVVPGLCHIWPELGNPRLY
AVPVAMGWRRVPAQEADLNPQALYV