Protein Info for GFF1833 in Methylophilus sp. DMC18

Annotation: HTH-type transcriptional repressor RspR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 PF00392: GntR" amino acids 14 to 74 (61 residues), 66.8 bits, see alignment E=1.1e-22 PF07729: FCD" amino acids 84 to 207 (124 residues), 80.2 bits, see alignment E=1.7e-26

Best Hits

KEGG orthology group: None (inferred from 37% identity to bja:bll6810)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (232 amino acids)

>GFF1833 HTH-type transcriptional repressor RspR (Methylophilus sp. DMC18)
MIKKEKPAKSSTVDALYSQLKQKIISFELYPGTRITELALAEMFGVSRTPIRQALQRLEI
EGFLSIRPKQGCFIRELDVTELMEYYEARIALELLIVESAVNAMSDKQVEQMMALWQPDK
HDAELQMGIDLGEKDESFHVGLALASDKPVLASILKNINHRIRVIRRLDLNADNRSQRTY
KEHYEILQLIKERDTTKAKQAMKRHIQRSREFAKTLTLTALARQKFLSTPSA