Protein Info for GFF183 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 PF00005: ABC_tran" amino acids 22 to 163 (142 residues), 108.1 bits, see alignment E=9e-35 TIGR01727: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain" amino acids 214 to 302 (89 residues), 91.8 bits, see alignment E=1.2e-30 PF08352: oligo_HPY" amino acids 215 to 280 (66 residues), 74.3 bits, see alignment E=1.2e-24

Best Hits

Swiss-Prot: 54% identical to Y2547_BRUO2: Putative peptide import ATP-binding protein BOV_A0347 (BOV_A0347) from Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)

KEGG orthology group: K02032, peptide/nickel transport system ATP-binding protein (inferred from 54% identity to gme:Gmet_0847)

MetaCyc: 47% identical to dipeptide ABC transporter ATP binding subunit DppF (Escherichia coli K-12 substr. MG1655)
ABC-8-RXN [EC: 7.4.2.9]

Predicted SEED Role

"Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (304 amino acids)

>GFF183 Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MCVHFKVGAGLFKPGKTLRAVEKVSLKIGENETLALVGESGSGKTTLGRVVAGLEVPTAG
QVRFRGERIQSSGKIQMVFQDPFSALDPRMLVGDIVAEPLRLLGEGTAAQRRERVRAMIE
QVRLPADAADRYPHEFSGGQRQRIAIARALISNPELIVADEPLSALDVSIQSQVLNLIMD
LKDSRKLALLFVSHDLAVVHHIADRVAVLYLGRLVEIAGRDELFSRPSHPYTRALLDAAP
RIGARRQRGASTLKGEIPSPINPPSGCVFHTRCPKATDICRSVEPVLEALSDRSGQWAAC
HFKE