Protein Info for GFF1819 in Variovorax sp. SCN45

Annotation: Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 PF02625: XdhC_CoxI" amino acids 13 to 70 (58 residues), 53.3 bits, see alignment E=2.2e-18 TIGR02964: xanthine dehydrogenase accessory protein XdhC" amino acids 18 to 265 (248 residues), 286.5 bits, see alignment E=9e-90 PF13478: XdhC_C" amino acids 119 to 264 (146 residues), 111 bits, see alignment E=5.6e-36

Best Hits

KEGG orthology group: K07402, xanthine dehydrogenase accessory factor (inferred from 93% identity to vpe:Varpa_4536)

Predicted SEED Role

"XdhC protein (assists in molybdopterin insertion into xanthine dehydrogenase)" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (269 amino acids)

>GFF1819 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family (Variovorax sp. SCN45)
MSGAVDQLLARLRHEDGVLVRVESTQGSAPREAGTWMAVWADGLTATIGGGQLEFQATKE
SRELLAGTRAPFDGIQRYPLGPSLGQCCGGVMFLSYQRITAADAPALQRELVAQLKPVAL
FGGGHVGAALARLLAALPFAVRWIDSRDGVFPEELPAQIDTEHSEPVQDAVAALAPGSRV
LIMSFSHAEDFDVVVACLKRMRERNDLPYVGLIGSKTKWATFSHRLEARGFGPDELARIT
CPIGVPGITGKEPEVIAVAVAAQLLQSLG