Protein Info for GFF1802 in Xanthobacter sp. DMC5

Annotation: Uric acid transporter UacT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 51 to 77 (27 residues), see Phobius details amino acids 102 to 124 (23 residues), see Phobius details amino acids 131 to 153 (23 residues), see Phobius details amino acids 181 to 199 (19 residues), see Phobius details amino acids 206 to 230 (25 residues), see Phobius details amino acids 253 to 278 (26 residues), see Phobius details amino acids 332 to 353 (22 residues), see Phobius details amino acids 360 to 381 (22 residues), see Phobius details amino acids 393 to 413 (21 residues), see Phobius details amino acids 423 to 442 (20 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 13 to 440 (428 residues), 395.9 bits, see alignment E=2.2e-122 PF00860: Xan_ur_permease" amino acids 16 to 409 (394 residues), 342.7 bits, see alignment E=1.2e-106 TIGR03173: xanthine permease" amino acids 20 to 443 (424 residues), 529.9 bits, see alignment E=3.8e-163

Best Hits

KEGG orthology group: K03458, nucleobase:cation symporter-2, NCS2 family (inferred from 91% identity to xau:Xaut_3292)

Predicted SEED Role

"Xanthine permease" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (463 amino acids)

>GFF1802 Uric acid transporter UacT (Xanthobacter sp. DMC5)
MSQTVHPVDEVLPAPKLAVLGLQHVLVMYAGAVAVPLIIGRALKLPPEQVAFLISADLFA
CGLATLAQCLGFLGVGIRLPVMMGVTFASVGPMLSMANDPSIGILGIYGSVIAAGIFGII
VAPFISRLLPLFPPVVTGTIIMVIGISLMRVGINWAGGGIPFLTQTIDGKVVQVANPNYG
QLQGLGIALFVLLVILALIRFGKGFVANVAVLLGIVAGAVLSTALGIMHFEKVGAAAWFD
VILPFHFGMPTFHLVPIITMCIVMIVVMIESLGMFLALSDMTGKPVDEKALARGLRADGV
GTLLGGIFNTFPYTSFSQNVGLVGVTGVRSRWVTVTGGIIMLGLGLLPKMAALVEAVPQV
VLGGAGLVMFGMVAATGARILTGVDFKTNRNNLFIVAISVGFGMIPLVSPNFFKALPHEL
HPLLESGILLCAIVAVVLNVFFNGVKKSSTEEIVAAAKQAEAH