Protein Info for GFF178 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: L-arabinose isomerase (EC 5.3.1.4)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 PF02610: Arabinose_Isome" amino acids 5 to 359 (355 residues), 598.7 bits, see alignment E=4e-184 PF11762: Arabinose_Iso_C" amino acids 363 to 476 (114 residues), 155.1 bits, see alignment E=6.2e-50

Best Hits

Swiss-Prot: 100% identical to ARAA_SALTY: L-arabinose isomerase (araA) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01804, L-arabinose isomerase [EC: 5.3.1.4] (inferred from 100% identity to stm:STM0102)

MetaCyc: 96% identical to L-arabinose isomerase (Escherichia coli K-12 substr. MG1655)
L-arabinose isomerase. [EC: 5.3.1.4]

Predicted SEED Role

"L-arabinose isomerase (EC 5.3.1.4)" in subsystem L-Arabinose utilization (EC 5.3.1.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (500 amino acids)

>GFF178 L-arabinose isomerase (EC 5.3.1.4) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MTIFDNYEVWFVIGSQHLYGAETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTSPDEI
TAICRDANYDDRCAGLVVWLHTFSPAKMWINGLSILNKPLLQFHTQFNAALPWDSIDMDF
MNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKEAHTRIGAWMRQAVSKQDTRQLKVCR
FGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSIGDGDINALIDEYESSYTLT
PATQIHGDKRQNVREAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQG
YGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAV
EEKPILDVQHLGIGGKEDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLP
KLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALDLNDMRQFAEIHDIEIAVIDNDT
HLPAFKDALRWNEVYYGFKR