Protein Info for GFF177 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Ribulokinase (EC 2.7.1.16)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01234: ribulokinase
  • amino acids 2 to 552 (551 residues), 882.2 bits, E=7.3e-270
• PF02782: FGGY_C
  • amino acids 291 to 501 (211 residues), 140 bits, E=8.9e-45

Best Hits

Swiss-Prot: 100% identical to ARAB_SALTY: Ribulokinase (araB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K00853, L-ribulokinase [EC: 2.7.1.16] (inferred from 100% identity to seh:SeHA_C0109)

MetaCyc: 91% identical to ribulokinase (Escherichia coli K-12 substr. MG1655)
Ribulokinase. [EC: 2.7.1.16]

Predicted SEED Role

"Ribulokinase (EC 2.7.1.16)" in subsystem L-Arabinose utilization (EC 2.7.1.16)

MetaCyc Pathways

• L-arabinose degradation I (4/4 steps found)
• D-arabinose degradation I (2/2 steps found)
• ribitol degradation I (1/2 steps found)
• D-arabinose degradation V (1/3 steps found)
• superpathway of pentose and pentitol degradation (17/42 steps found)

KEGG Metabolic Maps

• Pentose and glucuronate interconversions

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.16

Protein Sequence (569 amino acids)

>GFF177 Ribulokinase (EC 2.7.1.16) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MAIAIGLDFGSDSVRALAVDCATGDEIATSVEWYPRWQEGRYCDGPNNQFRHHPRDYMES
MEAALKAVLAQLSAAQRANVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWK
DHTAVEEADEITRLCHKPGKVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQAAVSWIEL
CDWVPALLSGTTRPQDIRRGRCSAGHKTLWHESWGGLPPASFFDELDPCINRHLRYPLFS
ETFTADLPVGTLCAEWAQRLDLPESVVISGGAFDCHMGAVGAGAQPNTLVKVIGTSTCDI
LIADKQSVGDRAVKGICGQVDGSVVPNFIGLEAGQSAFGDIYAWFSRVLSWPLEQLAAQH
PELKPQINASQKQLLPALTDAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLA
TDAPALFGGLVASTAFGARAIQECFTDQGIAVNNVMALGGIARKNQVIMQVCCDVLNRPL
QIVASDQCCALGAAIFAAVAAKVHADIPAAQQSMASAVERTLRPHPEQAQRFEQLYRRYQ
QWALSAEQHYLPTAAPAPTTPANQAILTH