Protein Info for GFF1759 in Variovorax sp. SCN45

Annotation: PQQ-dependent oxidoreductase, gdhB family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF07995: GSDH" amino acids 45 to 216 (172 residues), 149.7 bits, see alignment E=6.4e-48 amino acids 248 to 404 (157 residues), 198.3 bits, see alignment E=1.1e-62

Best Hits

KEGG orthology group: None (inferred from 89% identity to del:DelCs14_2308)

Predicted SEED Role

"PQQ-dependent oxidoreductase, gdhB family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (408 amino acids)

>GFF1759 PQQ-dependent oxidoreductase, gdhB family (Variovorax sp. SCN45)
MQLPKSALIPWLILGATPVLAQINAGNLPPTPSPPFKLTKVAQFDLPWRIAFLPDGRMLI
TEKIGRLYLATQSGQKLEVTGVPPVLYENQNGLLGVYLAPSFSSDGAIYLTYSEPGQIRG
TSSLALARATLKIGAGTASLEDLKVIWHDPVKGKGGQVGAAVAFSPDQKFLFLTAGDRQR
FTPAQDPNQPAGKILRLTLDGKPAPGNPMEGKTGARSVPVIDPPRDTEAAKTAPVVRTYV
FDGPNLTPSETWSSGHRTPYGLAFAPDGRLWELEHGPRGGDELNLIEPGKNYGWPLVSYA
VNYDGVPIASPDTRPDLVKPVIYWTPVLAPGNLMFYSGAMFPQWKGSAFATGLVSRALHR
IEVHGATATPAEHWTVGFRVRAVEQAPDGALWLIEDDHEGGLYRLTPN