Protein Info for GFF1713 in Pseudomonas sp. DMC3

Annotation: Sialic acid transporter NanT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 540 transmembrane" amino acids 34 to 53 (20 residues), see Phobius details amino acids 61 to 83 (23 residues), see Phobius details amino acids 95 to 114 (20 residues), see Phobius details amino acids 119 to 142 (24 residues), see Phobius details amino acids 164 to 187 (24 residues), see Phobius details amino acids 194 to 217 (24 residues), see Phobius details amino acids 249 to 274 (26 residues), see Phobius details amino acids 286 to 308 (23 residues), see Phobius details amino acids 317 to 336 (20 residues), see Phobius details amino acids 442 to 466 (25 residues), see Phobius details amino acids 485 to 505 (21 residues), see Phobius details amino acids 511 to 529 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 25 to 235 (211 residues), 110.5 bits, see alignment E=1e-35 amino acids 228 to 333 (106 residues), 27.2 bits, see alignment E=1.9e-10 PF07690: MFS_1" amino acids 29 to 333 (305 residues), 87.1 bits, see alignment E=1.1e-28

Best Hits

KEGG orthology group: None (inferred from 97% identity to pfo:Pfl01_3359)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (540 amino acids)

>GFF1713 Sialic acid transporter NanT (Pseudomonas sp. DMC3)
MSEHVQPLDAAGSAETSNATQKVIFASSLGTVFEWYDFFLYGALAAVISKQFFAGVNDTT
AFIFALMAFAAGFIVRPFGALVFGRLGDMIGRKYTFLATIILMGVATFCVGLLPTYASIG
IAAPIILVVLRMLQGLALGGEYGGAATYVAEHAPIGKRGFHTSWIQSTATLGLLLSLLVV
LGCRYFTGDQFEVWGWRIPFLLSIVLLGISTWIRLSLHESPAYLKMKEEGKTSKAPIRES
FGKWENLKVVLIALFSINAGQAVTFYAAQFYVLFFLTQFLKMDPAVANSLLIISVVIGAP
FFIFFGWLSDKVGRKPVLMLGLLLATALYFPIFKSLAHYANPAIDQASRQAPITVLADPA
TCTFQFDPVGKAKFDSPCDKVKTFLVKQGLPYSSVAAPAGSAVQVSVGDVKLDGFDEAAL
RGAITLAGYPQQADMQQINKPMIVALIVALIIISAMCYGPLAALMVELFPTRIRYTSMSL
PYHIGNGWFGGFLPTVSFALVVYTGDIFYGLWYPVLITGVSLVVGMICLRETKNIDLDKN