Protein Info for GFF1708 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868
Annotation: Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to RBSA_SALTY: Ribose import ATP-binding protein RbsA (rbsA) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG orthology group: K10441, ribose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 100% identity to sty:STY3896)MetaCyc: 97% identical to ribose ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-28-RXN
Predicted SEED Role
"Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.17
Use Curated BLAST to search for 3.6.3.17
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (501 amino acids)
>GFF1708 Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868) MDALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGS LLWLGKETTFNGPKSSQEAGIGIIHQELNLIPQLTIAENIFLGREFVNRFGKIDWKKMYA EADHLLAKLNLRFKSDKLVGELSIGDQQMVEIAKVLSFESKVIIMDEPTDALTDTETDSL FRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQFIAEREVATLTEDSLIEMMVGR KLEDQYPHLDNAPGEIRLKVDNLCGPGVNDVSFVLRKGEILGISGLMGAGRTELMKVLYG AMPRTSGYVTLDGHEVVTRSPQDGLANGIVYISEDRKRDGLVLGMSVKENMSLTALDYFS RAGGSLKHKDEQQAVGDFIRLFNVKTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILD EPTRGVDVGAKKEIYQLINQFKADGLSIILVSSEMPEVLGMSDRIIVMHEGHLSGEFTRE QATQEVLMAAAVGKLNRVNQE