Protein Info for GFF1657 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Transcriptional regulator, IclR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 PF09339: HTH_IclR" amino acids 4 to 55 (52 residues), 39.8 bits, see alignment 3.1e-14 PF01614: IclR" amino acids 127 to 247 (121 residues), 49.4 bits, see alignment E=4.3e-17

Best Hits

KEGG orthology group: None (inferred from 59% identity to bpy:Bphyt_4108)

Predicted SEED Role

"Transcriptional regulator, IclR family" in subsystem Homogentisate pathway of aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (290 amino acids)

>GFF1657 Transcriptional regulator, IclR family (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSGSLEKSLAILEYLAHCPDGAPLVQIATDLNQLRSGCHRTLHELIRFGYVRQLPQRGDY
ALTTKLASMGLSFLSRSGVVDIAQPVINRLAEATEELVRLAIVDGERLTLVAKAQGARSG
LKYDPDMGIDLRLSCSAAGHAWLMTLTEDAAIACVTRQGMGEPLHHGPNAPTSIKALLAM
LDEHRARGFSLIQDVYAPGMSSMAAPVARPKEPATGVIVIAGPSSRLTRQRMLGFGPLLQ
AAADELAAAGPASPLLKAANVGTWGNVSEAPARSRASDGAQSRLPPENRR