Protein Info for GFF1647 in Variovorax sp. SCN45

Annotation: Acyl-homoserine lactone acylase PvdQ (EC 3.5.1.-), quorum-quenching

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 742 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF01804: Penicil_amidase" amino acids 27 to 722 (696 residues), 327 bits, see alignment E=2e-101

Best Hits

Predicted SEED Role

"Acyl-homoserine lactone acylase PvdQ (EC 3.5.1.-), quorum-quenching" in subsystem Siderophore Pyoverdine (EC 3.5.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.-

Use Curated BLAST to search for 3.5.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (742 amino acids)

>GFF1647 Acyl-homoserine lactone acylase PvdQ (EC 3.5.1.-), quorum-quenching (Variovorax sp. SCN45)
MAAFAISCAVFGATPASARGDAPTTAIEIRRTADGIPHVRAGSWRGLGIGYGQAQAEDAL
CTLADAFVTYSGQRSLYFGAEGKPRTRSTFGEPVNLDLDFFFRAFAGPEAVEALKREQPA
DLNELIAGYAEGYNRHLRTLQARKPVRGVSAHACAGAPWVRAIGPEDIYRRMIAAGLAGG
YTRFVSEIVNAKPAALTPPVPADKLSLSSRLDIPVGDARGIGSNVLAFGQAATGERGGVL
FGNPHWYWGGPDRFYQAHLTLPGKLDAAGVSFLGIPVIMIGFNNDVAWSHTVSAARRFGL
FDLALDPADPTRYLVDGRSEPMQAQPLAVAVRRPDGSVDLVRRTLYRTRFGPVVDLGARN
PALAWSAHKALAIRDINADNPRIFRNFFRWDQARSLDEFMAIQREETAMPWVNTAAIGRG
DGRAWYADIGAVPGVGDELRSACATPLSKALAALDPAMPVLDGSRSTCEWQSAKNVAQPG
TMAADRMPGLLREDYVANMNDSYWLTNPEQPLTGFASILGGEGQPLSMRGQEGHRIAHEL
ANAGATSAKALADRVMQKTLEARASTADRFKVALLDGACAKDQVDIRRACEVLRRWPDRA
DANDRGALLWDAFWTRVQKIPAKDLYAQPFSASAPLRTPSAIHASDPRVAFALAGAVEDM
ARKGWALDMPLGQQRFARSEGRKLPLFGGCDAEGYFTVACANDGDYTMDDRSHGNTYLQV
CTSTGAACRRARCSRTANVKPR