Protein Info for GFF164 in Variovorax sp. SCN45

Annotation: DinG family ATP-dependent helicase CPE1197

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 767 PF06733: DEAD_2" amino acids 279 to 397 (119 residues), 44.9 bits, see alignment E=1e-15 PF13307: Helicase_C_2" amino acids 595 to 755 (161 residues), 128.9 bits, see alignment E=2.2e-41

Best Hits

KEGG orthology group: None (inferred from 82% identity to vpe:Varpa_2960)

Predicted SEED Role

"DinG family ATP-dependent helicase CPE1197" in subsystem DNA repair, bacterial DinG and relatives

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (767 amino acids)

>GFF164 DinG family ATP-dependent helicase CPE1197 (Variovorax sp. SCN45)
MDPDEPLPPVAHTVSVKALCAFGAKAGDLDLRFVPAPSALEGMAGHALVQHRRGGDYECE
VGLEATCGEMHVRGRADGYEFHKARVEEIKTFRGDFDAIRGNHRALHWAQARTYGWMLCE
RDGHDEMTVALVYFDIATGDETVLEEHHTRETLREHFELLCGRYAAWAATEAAHRTALDS
TLAALVFPYGSFRAGQRELAEAVYRAGAGGRCLMAQAPTGIGKTLATIFPLLKARAARKI
DKLFFLTAKTSGRPVALDALRVLDKGQGQGRLRVLELAAREKVCEYPDRACHGDACPLAK
GFYDRLPAAREQAAKVAWLDRQSLRDIGLAYEVCPYFLAQEMAHWADAIVGDYNYYFDSS
AFLYATMREADWRAAVLVDEAHNLLERARGMYTAELDGGALEEAHRMAPAVLRGPLARVF
REWDTVQQSQQADYETGDEIPERFLRTLQAANTAMAEHFAATPDASQGPLQRFFFDALHF
ARLAEAFGDHSVFERTLGATQQARRLAIRNLVPAPFLQGRFVEAASVTCFSGTLSPFEFY
RDALGLPEDTALLDVASPFHSKQLHVEVAMDVSTRFRDRAGSLRNVADIIGAQYERLPGN
YLAFFSSFDYLEKACAAFSMRHPGVPVWTQTRGMREAERHGFIARFEEGGQGIGFAVLGG
AFGEGIDLPGSRLIGAFVASLGLPQYNELNEITRERMQTRFGKGYEYTYLYPGLQKVVQA
AGRVIRTEDDRGVLHLLDDRFARAEIRELLPRWWHVRTAGVRISSDE