Protein Info for GFF1639 in Variovorax sp. SCN45

Annotation: Polyketide synthase modules and related proteins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1028 PF00668: Condensation" amino acids 32 to 314 (283 residues), 87.8 bits, see alignment E=1.4e-28 PF00501: AMP-binding" amino acids 451 to 779 (329 residues), 245.9 bits, see alignment E=1.3e-76 TIGR01733: amino acid adenylation domain" amino acids 472 to 850 (379 residues), 361.9 bits, see alignment E=2e-112 PF13193: AMP-binding_C" amino acids 834 to 908 (75 residues), 37.7 bits, see alignment 6.6e-13 PF00550: PP-binding" amino acids 941 to 1000 (60 residues), 51.3 bits, see alignment 2.3e-17

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1028 amino acids)

>GFF1639 Polyketide synthase modules and related proteins (Variovorax sp. SCN45)
MSVMTDPVETSFPLSPEQRMVPAGAERQLLLVGIEGMLDTARLRIAVEGVLQSHGALCAA
IRQVPGYRGPRLQPLDGMPPPKWQSADVAEAELAAWLEAFHREPLAAERGELVSVGLVRT
ADARHTLALSVNALAADRESLQNLFDQIAAVYLDEGSVESEDIFQYARFVEWRQDLLEGD
DADEGRAYWQRVAAEAATLAPPRLQGRAESVQPQAGRHRAGGAIDAALAGRVAARADALG
TQPETLLQAAWWLLLARLDGTGRFIGGWQHDCRRDYEPMQGAVGLFDKVLPVVVDVAMDE
SFAGWVGRFDAALAAHVDVQEYWSVDAPPLATHTVVGFASHEAPLPRGTEPRWRLTGLPD
PMPCFELALQAAWQTQGAELSLHADAAHYSQAAVERLLLQFLALLEAVVAQPDASVGALS
LVGPKERELLLARCGGERIDAGTQTVADRIAHWAQATPDAPALEAGEQRLNYRELDGRIN
RLAHWLAAQGVTPGSIVALNLPRSIELTVAIFAAWRVGAAYLPLEPEWPEARRASVLADA
RPALVLDAAAPPVPEGMPGTPPAHRISPQDLAYVLYTSGSTGKPKGVAIEQGHLLNYVAA
ASAAMRLDACRRWALTSSVVADLGNTALFGAFFNGACLVVAAEDDVKDADAFARFMAERE
IDAIKIVPSHLEALLECESPHLPRTLVLGGEAAPRALVERIARLAPQCAIYNHYGPTETT
VGVMVHAVPAGAQVSEQLPLTRVLANNRVHVLDEALGLVPAGALGEVYVGGAQLCRGYLN
REAADAFVADPFNPGQRLYRTGDLAYVLAEGGIRLAGRADHQVKIHGFRVEPAEVEAVLL
AQPGVRQAAVLAVPDAAGASALSAFFIADEVLADGRALRERLAAQLPAHMVPASFTAVDA
FARLPNGKIDRLALAAIVPAAAGHKARIEPRDALEAVLADGMASLLGSGPIGVEDDFFEL
GGHSLQVIKLVARIRKLLQVEVAAGVVFDHPTPAALAAALREDSDDAAQLEQRAQAHRQP
EEDMSETA