Protein Info for GFF1625 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Potassium efflux system KefA protein / Small-conductance mechanosensitive channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 70 to 89 (20 residues), see Phobius details amino acids 95 to 116 (22 residues), see Phobius details PF21088: MS_channel_1st" amino acids 74 to 114 (41 residues), 30.9 bits, see alignment 3.2e-11 PF00924: MS_channel_2nd" amino acids 116 to 180 (65 residues), 70.9 bits, see alignment E=1.2e-23 PF21082: MS_channel_3rd" amino acids 186 to 273 (88 residues), 30.2 bits, see alignment E=7.5e-11

Best Hits

KEGG orthology group: K03442, small conductance mechanosensitive channel (inferred from 58% identity to tbd:Tbd_0499)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (301 amino acids)

>GFF1625 Potassium efflux system KefA protein / Small-conductance mechanosensitive channel (Hydrogenophaga sp. GW460-11-11-14-LB1)
MNDQYIEIAARWWDTFGGFTTIAIRITLIVIAAWVTTGLLQRTVRKLRERIASRMDDRES
AKRAETLGRVIRYLIAVVISLVTAMLVLAELGVSVAPILGAAGVVGLAVGFGAQSLVKDY
FTGFFLLLEDQIRQGDVVQVGDHSGSVEEVTLRYVQLRDYSGNVHYVPNSTITTVINMSR
GFSNAVMDIGVAYRENVDEVMTVMREVGHQLRTDAAFESRLLADLEIAGVENWADSAVII
RCRFRTRPLEQWGIKREYLRRLKAAFDENGIEIPYPHMTVYAGQDRQGRAAAFQISNVPQ
S