Protein Info for GFF1618 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Sensory box histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 661 PF02518: HATPase_c" amino acids 146 to 243 (98 residues), 68.6 bits, see alignment E=6.5e-23 PF00072: Response_reg" amino acids 268 to 379 (112 residues), 83.4 bits, see alignment E=1.3e-27 amino acids 407 to 520 (114 residues), 91.5 bits, see alignment E=4.1e-30

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (661 amino acids)

>GFF1618 Sensory box histidine kinase/response regulator (Hydrogenophaga sp. GW460-11-11-14-LB1)
MRMAAQEQEKSLKALAGSIAHEMRNPLGQIRFSLHGVRNLLPRPIAHEEPEDAHPTLCPA
DLNKIYNHMAQGETAIDRGLQIISMTLDEVSGKPIDHASFEYLPASATTHKAVEEYSFDS
PGERNKVKVHVRNDFTLKANETAYLFILFNLIRNALFYFKQHPQATLTITVDAPHIRVRD
TGPGISPEVLGTLFGSFATSGKDGGTGLGLAYCQRTMQAFGGEIACDSVQGQYTEFTLRF
PTTTQAEIDQHEREVLALAAPFFEGKRILVVDDQALLRKATRALLDGLDCEHDEAEDGAQ
AIAKLRERTYDLVVMDLNMPALDGYATAEQIRQGAVPEQKNVAIMAYTSESAYMAHVKTE
KVGMIGFISKPCTRLELIKGLQAGLQAATYKALLDDATAAVLVGKTVLVADDGAFNRKIA
TTSLRSMGIEALEADNGLTALELLRRHPTIDAVLLDMEMPVMDGLQTAREIRKGHAALAR
RVPIIALTANGSDQHVAQAMAAGMDEFISKPFSPDQLRAVLIKVLTPGEPGRHFSAAAVA
AHANGVPLIHTQRLDQMRQLDSTLLRDCLTGHIEQMQAHFVQLEAQMASRNFPAFRTQLH
MLLGDAGAAGFHALHQFLRNEVYPTVADAQQWPEPETWLATARALYAQTERVVRRTYLKD
A