Protein Info for GFF1607 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: putative cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 PF00753: Lactamase_B" amino acids 32 to 228 (197 residues), 60.6 bits, see alignment E=1.1e-20

Best Hits

KEGG orthology group: None (inferred from 87% identity to pol:Bpro_0666)

Predicted SEED Role

"putative cyclase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>GFF1607 putative cyclase (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSKAFASQADLDDKKTTFEQLSPHCWAYTAEGDPNSGVIIGEKFIMVSDATATPAMAQDL
IKQIRTVSDKPIKYVLLTHYHAVRVLGASAYVAEGATEVIASRGTYELIVERGAEDMQSE
MERFPRLFRGSESVPGLTWPTLVVGDGRPGRQGSLTVDLGGVKVEIWHPGQGHTRGDTIA
WVEEEKVLFSGDLVEYEAGVYTGDAQLEEWPATLEALRALKAEAIVPGRGEAMKGRADVD
KALDYTKRWVTTLFQAGKEAAAAGMDLKTAMAHTRKSMDPVFGHVFIYEHCLPFDVSRAY
DEAKGIKNPRIWTAERDKEMWAALQG