Protein Info for GFF1602 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Arsenic efflux pump protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 transmembrane" amino acids 13 to 32 (20 residues), see Phobius details amino acids 41 to 58 (18 residues), see Phobius details amino acids 70 to 92 (23 residues), see Phobius details amino acids 104 to 131 (28 residues), see Phobius details amino acids 146 to 167 (22 residues), see Phobius details amino acids 188 to 205 (18 residues), see Phobius details amino acids 243 to 274 (32 residues), see Phobius details amino acids 283 to 305 (23 residues), see Phobius details amino acids 331 to 352 (22 residues), see Phobius details amino acids 364 to 388 (25 residues), see Phobius details amino acids 403 to 422 (20 residues), see Phobius details PF03600: CitMHS" amino acids 36 to 370 (335 residues), 192.3 bits, see alignment E=6.2e-61

Best Hits

KEGG orthology group: None (inferred from 74% identity to rfr:Rfer_0377)

Predicted SEED Role

"Arsenic efflux pump protein" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (426 amino acids)

>GFF1602 Arsenic efflux pump protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MPTTSAFHHTATDWGIVAVFAVVYLGMFLGGLPRLKLDRSGVALLGAIAVIGLSGLPVED
AARSVDLPTIVLLFAFMVVSAQMRLGGFYGAVTRQVGALPLSRNGLLAALIVVSGALSAV
FSNDIICLAMTPVVARLCLQRGINPLPFLIGLACAANIGSAATLIGNPQNMLIGSVLQLP
FGGYVRQALPPVLISLLLLWLWLAFGPGARTASAAESAGQPFAAVAEAPPEEPDFDAWQT
TKGLVVAGALMLIFLFTDWPRDVAALVGAGLLLLSRRLHSSHVLGLIDWPLLLLFMGLFV
VNHAFETTGLAAQAVAWLGTQGVHLAEPGPLLVVSAVLSNLVSNVPAVMLLLPHLGGSSG
QAGAMLALVTTFAGNLLLVGSIANLIVADLARQQGIVIDWKRHAITGIPVTLLTLAVVWA
WMRWAL