Protein Info for GFF16 in Variovorax sp. SCN45

Annotation: Cellulose synthase (UDP-forming) (EC 2.4.1.12) / Efflux transport system, outer membrane factor (OMF) lipoprotein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1144 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 36 to 52 (17 residues), see Phobius details amino acids 65 to 86 (22 residues), see Phobius details amino acids 376 to 397 (22 residues), see Phobius details amino acids 408 to 427 (20 residues), see Phobius details amino acids 479 to 501 (23 residues), see Phobius details amino acids 513 to 531 (19 residues), see Phobius details amino acids 661 to 680 (20 residues), see Phobius details PF13641: Glyco_tranf_2_3" amino acids 116 to 344 (229 residues), 60.8 bits, see alignment E=6.3e-20 PF00535: Glycos_transf_2" amino acids 120 to 289 (170 residues), 72.4 bits, see alignment E=1.4e-23 PF03552: Cellulose_synt" amino acids 173 to 289 (117 residues), 30 bits, see alignment E=6.5e-11 PF13506: Glyco_transf_21" amino acids 181 to 343 (163 residues), 33.5 bits, see alignment E=8.8e-12 PF13632: Glyco_trans_2_3" amino acids 200 to 409 (210 residues), 72 bits, see alignment E=1.8e-23 TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 674 to 1129 (456 residues), 306.4 bits, see alignment E=1.7e-95 PF02321: OEP" amino acids 725 to 903 (179 residues), 61.4 bits, see alignment E=3.2e-20 amino acids 945 to 1127 (183 residues), 87.4 bits, see alignment E=3.3e-28

Best Hits

Predicted SEED Role

"Cellulose synthase (UDP-forming) (EC 2.4.1.12)" (EC 2.4.1.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.12

Use Curated BLAST to search for 2.4.1.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1144 amino acids)

>GFF16 Cellulose synthase (UDP-forming) (EC 2.4.1.12) / Efflux transport system, outer membrane factor (OMF) lipoprotein (Variovorax sp. SCN45)
MFELIDTPEFRVNLMVVGLALIMVFHARADRASHRVLFGFLTALVLVRYVAWRLSETLPP
ADLGFGTLMGWVFLVFEMVSILYTLLSIQMLSRRRDNHAQADAGEAMLRKRGADVPAVDV
FICTYNEEIGVLEKTILAAQAIDYPHVNVWVLDDTRRDWLRDYCARKGVHYARRPDNTHA
KAGNLNNGLRQSAGQTNAPYILVLDADFAPHRNIVYRVLGLFEDPKSKVGLVQTPQFYYN
ADPIQHNLRATDSWVDEQRVFFDVLQPAKDAADVAFCVGTSFIVRRDAITAAGGFPTGSV
CEDIYTTYTLMRFGWVTRWLNERLSNGLSADSVIDYINQRSRWCLGTIQVALLRDGPLRG
RGYSFAARLHYVHGLLHWLTKPFILLILAAPALYWYTGASAFHATPRAFAMYGLPPLVMF
WGYTYWISQRRCLPVFTEVTQIVAAMAVTRTIVSSLIRPFGRPFKVTAKGQDRSRTVVHW
NLVAVFGALIVAMEMGALGAIGGSMTTGDMLNVVWTFIATVYCLAALIACIDRPRPEHDE
RFPYDAATTVRSAAGVGTARFMEIAGDGARLCNSASLGRIAIGQALDIHVDHVGWVAASV
TGRSDAGTELAFAHDEAVHDRLVRHVFSLPPSHVATQVKPGRAVLAFMDSAGWRVPTMPR
MLVSSAPMLTVLLVAVLVLSGCNLTPPLKPAEVDVPVQWAEGKAGTDVAPMAWQSFVRDD
ELRGLIATALAQNRDLRVYAAKAREARAVYAGTRSSLFPEIGLVGSAGRGNQITSLSSTG
VVTNSQVVGSVGNTYAVQAGITAYELDFFGRVDSGVKQAGSQAVASERDFAAARMNLVGE
VANAYLTLRADRALLALAESDFATQTDSTGVMERARKAGGTSDLDLLRSQSLVQRASVQR
EEFRMRVGQDLQWLTVLVGQPVPVSTGTRRPWPDRAVADVPVGLPASLLQRRPDLLAAYA
RVEAANSGIGAAKAAFYPSFSLTAVGGGLSSEFSSLLNSGNRSWATVLGVSLPIFDWGRR
SANLSANEERLAAAMAGYEYAVQQALRETANALIADSHLRPQLEAQQARVLSLQRVAAIS
RTRFRNGLEDYFAGADAQRELYIEQRQWIELQLKQAVNTVSLYKALGGGWEDAPAPVAAA
TAPR