Protein Info for PS417_08045 in Pseudomonas simiae WCS417

Annotation: uracil permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 transmembrane" amino acids 28 to 48 (21 residues), see Phobius details amino acids 54 to 76 (23 residues), see Phobius details amino acids 83 to 102 (20 residues), see Phobius details amino acids 108 to 130 (23 residues), see Phobius details amino acids 137 to 161 (25 residues), see Phobius details amino acids 173 to 191 (19 residues), see Phobius details amino acids 202 to 222 (21 residues), see Phobius details amino acids 240 to 261 (22 residues), see Phobius details amino acids 324 to 343 (20 residues), see Phobius details amino acids 352 to 370 (19 residues), see Phobius details amino acids 382 to 404 (23 residues), see Phobius details amino acids 410 to 433 (24 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 20 to 431 (412 residues), 338.2 bits, see alignment E=7.5e-105 PF00860: Xan_ur_permease" amino acids 22 to 401 (380 residues), 309.9 bits, see alignment E=1.1e-96 TIGR03173: xanthine permease" amino acids 24 to 434 (411 residues), 506.5 bits, see alignment E=4.9e-156

Best Hits

Swiss-Prot: 40% identical to UACT_ECOLI: Uric acid transporter UacT (uacT) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to pfs:PFLU1628)

MetaCyc: 40% identical to urate:H+ symporter (Escherichia coli K-12 substr. MG1655)
RXN-5076; TRANS-RXN0-530

Predicted SEED Role

"Xanthine permease" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UI47 at UniProt or InterPro

Protein Sequence (500 amino acids)

>PS417_08045 uracil permease (Pseudomonas simiae WCS417)
MTIPKASPQRPEDENLGVAANMAYGLQHVLTMYGGIVAVPLIVGQAAGLSPADIGLLIAA
SLFAGGLATLLQTLGLPFFGCQLPLVQGVSFAGVATMVAIVGSDGAGGVPAILGAVMAAS
FIGLLITPVFSRITKFFPPLVTGIVITTIGLTLMPVAARWAMGGNSRAADFGSMSNIGLA
ALTLVLVLLLSKIGSATISRLSILLAMVIGTVIAVFLGMADFSGVTQGPMFGFPAPFHFG
MPTFHVAAIISMCIVVMVTLVETSADILAVGEIIDTKVDSKRLGNGLRADMLSSMFAPIF
GSFTQSAFAQNVGLVAVTGVKSRFVVATGGLFLVILGLLPFMGRVIAAVPTSVLGGAGIV
LFGTVAASGIRTLSKVDYRNNMNLIIVATSIGFGMIPIAAPSFYDHFPSWFATIFHSGIS
SSAIMAILLNLAFNHFTAGNSDQQSVFVAGTERSLCFRDVSELRDGDYFKGGKLFDAEGR
EIPLVADVSRKAHKAETTEV