Protein Info for GFF1565 in Xanthobacter sp. DMC5

Annotation: Adaptive-response sensory-kinase SasA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 884 transmembrane" amino acids 36 to 58 (23 residues), see Phobius details amino acids 69 to 91 (23 residues), see Phobius details amino acids 108 to 130 (23 residues), see Phobius details amino acids 146 to 167 (22 residues), see Phobius details amino acids 178 to 195 (18 residues), see Phobius details amino acids 215 to 234 (20 residues), see Phobius details amino acids 253 to 286 (34 residues), see Phobius details amino acids 308 to 328 (21 residues), see Phobius details amino acids 357 to 376 (20 residues), see Phobius details amino acids 382 to 404 (23 residues), see Phobius details amino acids 424 to 447 (24 residues), see Phobius details amino acids 454 to 473 (20 residues), see Phobius details amino acids 567 to 588 (22 residues), see Phobius details amino acids 606 to 627 (22 residues), see Phobius details PF00512: HisKA" amino acids 663 to 725 (63 residues), 55.4 bits, see alignment 5.1e-19 PF02518: HATPase_c" amino acids 767 to 876 (110 residues), 95.9 bits, see alignment E=2.1e-31

Best Hits

KEGG orthology group: None (inferred from 82% identity to sno:Snov_1178)

Predicted SEED Role

"Two-component hybrid sensor and regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (884 amino acids)

>GFF1565 Adaptive-response sensory-kinase SasA (Xanthobacter sp. DMC5)
LETPELPALRSYHSWIANETLEDYSLRYTARSFRRWSPFVIANTALGGISFLALETIGGS
ITLNYGFTNASLAILVVSVFIFVTSLPIAYYSSKYGVDLDLLTRGAGFGYIGSTITSLIY
ASFTFIFFALEGAIMAQALKLYFDLPLVLGYILSSLVIIPVTLMGITMISRLQMATQPLW
LAMMVLPFVMIWLKAPDEVAAWSRFVGRDTGSSGFDALAFGAAVSVMCSLVVQIGEQADY
LRFLPEKKASNRLAWWGAVVMAGPGWIVIGGLKILAGGLLAVLVLGAGLPHQTALEPIYM
YLVAYQHVFDNPALALFCATLFVLVSQVKINVTNAYAGSLAWSNFFSRVTHYHPGRVVWL
VFNILISLLLMLLGIFETLDVVLAVYSNIAMAWVGAIIADLLVLKPLKVSPGFIEFKRAH
LHDFNPVGCGGMAAGSLVSLLAFTGVFGPAVEAYAAPLSFLIAFLTAIAIGFATRGRYYL
ARPPVDASLAQGTGPVLRCEICDHGYERDDMAYCSFYERPICSLCCSLDAHCHDACKKSR
QDLESSRSRYFGEGFRRRIAPHMPQRLLKVGGVLVALTVVTAALFLLTYRLIDPGAETPR
LDNGGLLLRVFLAMLPLLAISAWWIVLSNESRELAERNLVGSLEKLNETREELTRSERLA
AIGQLTATVSHELRNPLGTLATSVAVLQRTSALSGDRERGELDRIQRNVRRCVRIIEDLL
EFSRRPDVSMVPLALDAWIAEQASDLRALSGVELALDLDCDRIIEADGERLRQVLVNLVQ
NAMQAVLERPAGAPPGRVAIATAAEGERVRITVIDNGVGMDDEVRRRLFEPLFSTKPFGL
GLGLALVKRITERHGGSVSISSEPGRGTRVDITLPAAGEHADAA